Various medical situations, such as arthritis and Morton’s neuroma, could cause inflammation or nerve irritation during the impacted area. Surplus entire body fat increases force on the metatarsal bones, when preceding foot injuries may change foot composition or function.  Sesamoid pain on the ball on the foot though standing or https://www.theorthopaedicandpainpractice.com/effective-treatments-for-ball-of-foot-pain/