Pharmacological inhibition with the ataxia telangiectasia and Rad3-similar protein serine/threonine kinase (ATR; also called FRAP-connected protein (FRP1)) has emerged as a promising strategy for cancer treatment that exploits synthetic lethal interactions with proteins associated with DNA damage repair service, overcomes resistance to other therapies and enhances antitumour immunity.... https://johns988epa1.thechapblog.com/profile