XPO1 inhibition by selinexor resulted in nuclear accumulation of p53, producing mobile cycle arrest and apoptosis. Also, inhibition of XPO1 lead to the cytoplasmic retention of p21 and suppression of survivin. Orally administered selienxor induced sizeable inhibition of tumor expansion in xenograft models of gastric most cancers. Additionally, mixture of https://bustere196waf9.bloggadores.com/profile